Daily OTC Pearl: Glycerin Suppositories

Glycerin Suppositories are indicated for acute and temporary episodes of constipation.

OTC/Lifestyle Pearl of the Day: Glycerin Suppositories

Indication: Glycerin Suppositories are used in the treatment of acute and temporary episodes of constipation and is suitable for use in adults, children, and infants.


  • Dosage: Glycerin Suppositories come in 1 g, 1.5 g, 2 g, 2.1 g, and 2.8 g dosages.
  • Administration: Patient should lie on left side with knees bent. The protective wrapping around the suppository should be removed before inserting into the rectum. Gently insert tip into rectum with slight side-to-side movement, with the tip of suppository pointing toward navel. For liquid suppository, squeeze bulb until all liquid is expelled and then discard the unit.
  • Glycerin Suppositories allow for the direct application of glycerol to the bowel contents.Glycerol helps to make the stool softer and easier to pass out of the colon.
  • Directions for use: Insert one suppository well into the rectum and leave for 15 to 30 minutes. It is not necessary for the whole suppository to melt for the required effect to take place.
  • Adverse effects (AEs): The most common AEs associated with the use of Glycerin Suppositories include distension, abdominal cramps, flatulence, and diarrhea if used in excess dosage.


Glycerin Suppositories | myVMC