Daily Medication Pearl: Mesalamine (Apriso)

Article

Mesalamine (Apriso) is a locally acting aminosalicylate indicated to treat and prevent flare-ups of ulcerative colitis.

Medication Pearl of the Day: Mesalamine (Apriso)

Indication: Mesalamine (Apriso) is a locally acting aminosalicylate indicated for the maintenance of diarrhea, upper abdominal pain, nausea, nasopharyngitis, flu or flu-like remission of ulcerative colitis in adults.

Insight:

  • Dosing: Four capsules once daily (1.5 g/day) in the morning with or without food. Do not co-administer with antacids.
  • Dosage forms: Extended-release capsules 0.375 g.
  • Adverse events: The most common adverse reactions (incidence ≥3%) are headache, diarrhea, upper abdominal pain, nausea, nasopharyngitis, flu or flu-like remission of ulcerative colitis in adults, illness, and sinusitis.
  • Mechanism of action: The mechanism of action of mesalamine is unknown but appears to be local to the intestinal mucosa rather than systemic.
  • Manufacturer: Catalent Pharma

Sources:

label (fda.gov)

apriso image - Google Search

Related Videos
Laboratory test tubes and solution with stethoscope background | Image Credit: Shutter2U - stock.adobe.com
Image credit: Andrea Izzotti
Inflation Reduction Act is shown using the text and the US flag - Image credit: Andrii | stock.adobe.com
Pharmacy Interior | Image Credit: Tyler Olson - stock.adobe.com
Male pharmacist selling medications at drugstore to a senior woman customer | Image Credit: Zamrznuti tonovi - stock.adobe.com
Pharmacist assists senior woman in buying medicine in pharmacy - Image credit: Drazen | stock.adobe.com
Pharmacy, medicine and senior woman consulting pharmacist on prescription. Healthcare, shopping and elderly female in consultation with medical worker for medication box, pills or product in store - Image credit: C Daniels/peopleimages.com | stock.adobe.com
Image credit: fidaolga - stock.adobe.com
Pharmacists checking inventory at hospital pharmacy- Image credit: Jacob Lund | stock.adobe.com
Young male pharmacist giving prescription medications to senior female customer in a pharmacy | Image Credit: Zamrznuti tonovi - stock.adobe.com
© 2023 MJH Life Sciences

All rights reserved.