Daily Medication Pearl: Fosamprenavir Calcium (Lexiva)

Medication Pearl of the Day: Fosamprenavir Calcium (Lexiva)

Indication: Fosamprenavir calcium (Lexiva) is an HIV protease inhibitor indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.

Insight:

• Dosing:Therapy-naive adults, Lexiva 1400 mg twice daily; Lexiva 1400 mg once daily plus ritonavir 200 mg once daily.
• Dosage forms: 700 mg tablets and 50 mg/mL oral suspension.
• Adverse events:In adults, the most common adverse reactions (incidence ≥4%) are diarrhea, rash, nausea, vomiting, and headache.
• Mechanism of action: Fosamprenavir is an antiviral agent.

Source: Lexiva Label (fda.gov)