Despite many advances in treating diabetes, the majorityof adults with the disease have not reached the appropriateHbA1C goal. Reporting in the American Journal ofManaged Care (April 2005), Kaiser Permanente conductedthe first head-to-head analysis of the use of all currentavailable treatments for diabetes. The study involved 4775members of Kaiser Permanente Northern CaliforniaGroup.
The study's findings showed that >80% of badly controlledadults with type 2 diabetes who started new antidiabetictherapies did not achieve recommended glycemictargets (HbA1C ≤7%) within 1 year. The researchers suggestedthe need for more aggressive and earlier intensificationof established therapies; less waiting time withquick progression from single therapy to combination therapywith or without insulin; and further investigation ofways to incorporate behavioral change.