
Pirtobrutinib is the first and only non-covalent BTK inhibitor to be approved by the FDA and is indicated for adult patients who already received at least 2 prior lines of therapy.

Pirtobrutinib is the first and only non-covalent BTK inhibitor to be approved by the FDA and is indicated for adult patients who already received at least 2 prior lines of therapy.

Despite nearly one-third of reversible dementia cases being drug induced, cognitive safety is a neglected aspect of clinical trials.

Three classes of drugs could be 2 to 5 times more effective than ibuprofen for the treatment of migraine attacks, according to results of a study.

Fewer individuals have received the flu shot this season, compared to previous years.

Although personality was linked to cognitive performance on tests, it was not linked to dementia pathophysiology.

In mice with heart failure, radiation therapy demonstrated improved heart function, specifically in the left ventricle, and reduced inflammation in the heart.

The proportion of prescriptions by a 340B-affiliated physician increased from 9.4% in 2013 to 19.3% in 2020, but the prescriptions filled by 340B pharmacies increased from 18.4% to 49.9%.

The study authors reported a 50% uptick in pharmacist prescribing was associated with approximately $1.137 trillion in savings over a 30-year time period.

Iberzaplstat was non-inferior to standard of care vancomycin, was safe and tolerable, and will advance into a phase 3 trial.

Further research of these mechanisms could be significant in developing future strategies to disrupt the viral persistence in individuals living with HIV.

Patients with this genetic variant have impaired neuronal excitability, a trait that has been linked to malfunctional synapses.

The study also showcases a significant decline in asthma mortality rates in China, which were previously higher than the United States from 1990 to 2019.

If approved, this combination will become a first-line treatment option for patients who are cisplatin eligible.

The aim of developing GP40141 as a biosimilar is to help reduce the cost of the drug and make treatment more affordable for those with idiopathic thrombocytopenic purpura, according to investigators.

Non-expansion states had an increase in prescriptions after PA removal at 27.3% and Medicaid expansion states demonstrated a 22% decrease in prescriptions.

According to the authors, current HIV care methods demonstrate that the mean age at death for Black MSM was 68.8 years, whereas the mean age for White MSM was 75.6 years.

Following acoustic stimulation intervention, many patients experienced a reduction in neurobehavioral symptoms.

Investigators believe lowering cholesteryl ester levels could help prevent brain damage and behavioral changes, reducing the risk of Alzheimer disease.

Although involvement of a cardiologist for heart failure has been associated with reduced rates of in-hospital mortality, not all patients see a cardiologist when hospitalized, according to the investigators.

Many workers don’t advertise their level of loneliness, nor do they know the impact of loneliness on their well-being.

Exclusions of medication are often focused on high-cost specialty formularies, resulting in fewer options for patients who need them.

Marlo Blazer, PharmD, BCOP, discusses the collaborative nature of the pharmacist's role within the oncology care team.

An animal study shows that early-life stress may increase risk-taking behaviors in adulthood; in humans, this could translate to risk of substance use disorder.

Patients with uncontrolled chronic obstructive pulmonary disease and type 2 inflammation had significantly better lung function at least a year into dupilumab regimen.

Nacre may combat cortical bone loss and improve bone strength to reduce risk of fragility fractures.

These findings could make a significant difference in treating patients with Barth syndrome, which is an incurable genetic disease.

Neuroimaging showed that people who lacked sleep had altered risk-taking behaviors.

With wider testing available, diagnosing COVID-19 has become easier and many patients now have access to important treatment options.

There is a great need to protect families and children that are commercially insured following the COVID-19 pandemic.

Further research is necessary to better understand the development and factors that contribute to CBC after PBC treatment.