The Pharmacy Times® Zoster Resource Center is a comprehensive resource for clinical news and expert insights on the reactivation of the chickenpox virus in the body, which causes a painful rash.
Advanced Age and Multiple Comorbidities May Be Factors in Poor Prognosis for HZO
Herpes zoster ophthalmicus develops when a varicella-zoster virus infection is reactivated, generally in those who are immunocompromised, and leads to chronic ocular complications.
Amyloid Potentially Involved in VZV Vasculopathy
The researchers based this conclusion on the analysis of VZV-infected primary human brain vascular adventitial fibroblasts (HBVAFs), which are among the first arterial cells infected in VZV vasculopathy.
Pharmacy Clinical Pearl of the Day: Encephalitis
Common viruses causing encephalitis include herpes virus, enteroviruses, amd mosquito- and tick-borne viruses.
Recombinant Zoster Vaccine May Slightly Increase Risk of Guillain-Barré Syndrome
Study notes risk-benefit balance remains in favor of vaccination with recombinant zoster vaccine.
Safety Profile of Upadacitinib Shows Drug May Increase Herpes Zoster Risk
Study evaluates the safety profile of upadacitinib at 15 mg and 30 mg once daily for patients with moderately to severely active rheumatoid arthritis.
Shingles Doesn’t Care: Re-Engaging Older Patients to Get Vaccinated
Pharmacy Clinical Pearl of the Day: Bell’s Palsy
Viruses that have been linked to Bell's palsy include those that cause cold sores and genital herpes (herpes simplex); Chickenpox and shingles (herpes zoster); and infectious mononucleosis.
Trial Evaluates Safety Concerns With Live Attenuated Zoster Vaccine in Patients Receiving Tumor Necrosis Factor Inhibitor Therapy
The objective of this study was to evaluate the safety and immunogenicity of the live attenuated zoster vaccine (ZVL) in patients receiving TNFis, according to the study authors.
Study Examines Herpes Zoster Reactivation Following COVID-19 Vaccination
A new study examined 3 different cases of chronic urticaria being treated with cyclosporine and patients who developed reactivation of recurrent herpes zoster (HZ) following COVID-19 vaccination.
Pharmacy Quiz: Test Your Knowledge on Genital Herpes
Ten quiz questions to assess your knowledge on common symptoms and treatments for genital herpes.
Study: OPTN Suppresses Growth of Herpes Simplex, Protects Nervous System
Research results show a possible link between herpesviruses and neurodegenerative diseases, such as Alzheimer disease, ALS, and glaucoma.
Pharmacy Quiz: Test Your Knowledge on Shingles
Ten quiz questions to assess your knowledge on common symptoms and treatments for shingles.
Study: Possible New Antivirals May Be Protective Against Herpes, Other Infections
They added that side chains are linked to nitrogens in the molecular backbone, forming a structure that resists enzymes.
Pharmacy Clinical Pearl of the Day: Shingles Infection
After chickenpox, the virus stays inactive in nerve tissue near the spinal cord.
Shingles Is a Concern At All Ages
Anyone, even young people, can get infected, so the varicella or zoster vaccines offer the best prevention.
mRNA Vaccine Against COVID-19 May Result in Herpes Zoster Development in Rare Cases
The study sample included female patients between 36 and 61 years of age, and in all cases, the baseline rheumatic disease was either mild or stable under medical treatment.
Children with Systemic Lupus Erythematosus, Lupus Nephritis May Be at Increased Risk of Herpes Zoster
Complications of varicella-zoster virus in patients with lupus may be attributable to immunological abnormalities, lymphopenia conditions, and immunosuppressive therapies.
FDA Approves Expansion of Shingrix for Prevention of Herpes Zoster in Immunocompromised Adults
Zoster vaccine recombinant, adjuvanted has been approved by the FDA for the prevention of herpes zoster in adults 18 years of age and older who are, or will be, at an increased risk of shingles because of immunodeficiency or immunosuppression.
Herpes Zoster Associated With Elevated Risk of Stroke, Cerebrovascular Events
This risk decreased gradually according to age and length of time after an HZ episode, but epidemiological studies and the pathology of VZV vasculopathy both indicate that HZ is a key risk factor for stroke up to 1 year following an HZ episode.
Study: Some Systemic Anti-Psoriasis Therapies Increase Risks of Herpes Zoster
Although researchers identified 3 agents that increased the risk of herpes zoster among patients with psoriasis, they also found 2 therapies that seemed to decrease the risk.
Herpes Zoster Has Various Treatment Options
Antiviral medications, including Acyclovir, famciclovir, and valacyclovir, are effective if taken as soon as the diagnosis and can shorten the duration of the infection while improving symptoms.
Study Models the Effect of Herpes Infection on Fetal Brain Development
HSV-1 can spread to the fetal brain during pregnancy and cause lifelong neurological problems, such as cognitive dysfunction, learning disabilities, and dementia.
Intestinal Worm Infection Remotely Worsens Outcomes for Sexually Transmitted Viral Infections
According to the study, helminth-infected mice developed significantly more severe symptoms after infection with a genital herpes virus (herpes simplex virus), results that the researchers believe are also transferrable to humans.
Patients Presenting With Herpes Zoster May Have Underlying COVID-19 Infection
The authors of the study suggest that any patient with HZ should be tested for COVID-19, even if the individual has mild symptoms or no history of upper respiratory symptoms.
Expert: Pharmacists Are ‘The Heroes of 2021,’ Leading the Charge on Helping to Heal Our Nation
The efforts of pharmacists to keep their doors open during the pandemic, build COVID-19 testing sites, and prepare for and administer COVID-19 vaccinations took extraordinary investment and determination.
Pharmacy Technician Role Expands
The COVID-19 pandemic has created challenges and opportunities, and this requires agility and flexibility.
Non-Live Recombinant Vaccine for Herpes Zoster Shows Greater Efficacy, Broader Applicability Than Live Attenuated Vaccine
A study comparing the efficacy of the 2 commercially available herpes zoster (HZ) vaccines, the live zoster vaccine and the non-live recombinant zoster vaccine, found that RZV has both higher efficacy and broader use cases, according to the authors.
Differences in Herpes Virus Symptoms Linked to Strain Gene Expression Variations
Researchers found that viral variants expressed their genes at different rates and quantities, which likely contributes to the different timing and severity of symptoms within hosts.
As Herpes Zoster Incidence Increases, Treatment and Prevention Methods Are Essential
In addition to prevention with a live attenuated vaccine, treatment options for herpes zoster can include antivirals or symptom management with corticosteroids or analgesics.
Herpes Zoster May Be A Sign of COVID-19 in Pregnancy
Experts say the clinical presentation of herpes zoster in pregnant women should be carefully monitored and reported for further assessment, especially if it is associated with other signs of COVID-19.
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