CLINICAL ROLE -
Biosimilars Found to Produce Cost Savings Despite Increased Consumption Volume
Availability of TNF-alpha inhibitor biosimilars in Southern European markets led to lowered costs within the drug class, even after an increased consumption volume for these therapies.
Fecal Transplant Offers Multiple Benefits for Patients With C Diff, COVID-19 Co-Infection
Study shows a statistically significant improvement in inflammatory syndrome after a fecal microbiota transplant in patients coinfected with COVID-19 and clostridioides difficile.
Study Finds Nearly 3 in 10 Individuals With Chronic Pain Use Cannabis
Most individuals who used cannabis to manage their chronic pain reported using it in place of other pain medications, including opioids.
Mortality, Adverse Medication Events, Length of Hospital Stay Rises as More Organ Systems are Impacted by MIS-C Post-COVID-19
Multisystem inflammatory syndrome typically presents approximately 1 month after a COVID infection, occasionally resulting in cardiac complications in previously healthy children.
Study Evaluates Impact of Pharmacy Liaison-Patient Navigators on ACO Hospital/ED Admission Rates
Enhanced care involves a pharmacy technician serving as a patient navigator who screens for health-related social needs quarterly and helps to connect patients with community resources.
Telemedicine Associated With Direct, Indirect Cost Savings for Patients With Cancer
During the COVID-19 pandemic, patients were able to utilize telehealth services to receive care more conveniently, which may reduce the cost of care.
Hospitalizations for Mental Health Conditions Increased During the Pandemic Among Adolescents
Study notes that evaluating changes in the proportion of hospitalizations for mental health conditions among adolescents is vital to ensure the prioritization of public health programs that address psychiatric health care needs that emerged during the COVID-19 pandemic.
Depression Associated With Lower Medication Adherence Post-Percutaneous Coronary Intervention
Patients with depression were significantly less likely to have adequate 12-month adherence to antiplatelets, β-blockers, and statins than those without depression.
Outpatient Behavioral Health Treatment Associated With Reduced Medical and Pharmacy Spending
Investing in outpatient behavioral health treatment pathways found to be a cost-effective measure to better manage both medical and behavioral conditions.
Study Finds Distinct Differences in Cytokine Response in Rhinovirus vs RSV
Respiratory syncytial virus- and rhinovirus-induced wheezing illnesses differ from each other at multiple levels.
Observational Study Designs of Metformin in Type 2 Diabetes Insufficient to Residual Confounding
Commonly published metformin study designs in patients with type 2 diabetes may not be sufficiently addressing residual confounding.
Substance Use Linked With Antiretroviral Therapy Non-adherence Among People With HIV
Due to the correlation between virologic suppression and antiretroviral therapy adherence, understanding the impediments of adherence is of the utmost importance.
Impact of Flavonoids on Fatigue in Patients with RRMS
A recent study showed that flavonoid-rich cocoa improved fatigue by 45% in patients with relapsing and remitting multiple sclerosis.
Study Finds Early Intensive Therapy Better for Long-Term MS Outcomes
In a real-world setting, long-term outcomes were more favorable following early intensive therapy when compared with first-line moderate-efficacy diseased modifying therapy.
Lawmakers Deny Proposal to Require Drug Pricing in Television Ads
A federal appropriations bill will not include bipartisan provision that would have required drug manufacturers to be more transparent with costs to consumers after it was blocked by House Republicans.
How Can Bioinformatics Determine Immunotherapy Response?
A recent study discovered a new way to use bioinformatics to determine how a patientâ€™s immune system responds to immunotherapy.
New Test Can Identify NSCLC Patients Most Likely to Benefit from Immunotherapy
A blood-based test to assess tumor mutational burden was recently discovered as being able to accurately identify patients with nonâ€“small cell lung cancer (NSCLC) who could benefit from checkpoint inhibitor treatment.
Keytruda Succeeds in Phase 3 Trial for Head and Neck Cancer
KEYNOTE-048 has met a primary end point of overall survival.
Immune Checkpoint Inhibitors More Effective in Men Than Women for Advanced Cancers
A recent systematic review and meta-analysis found that men with advanced cancers respond better than women to treatment with anti-PD-1 or anti-CTLA-4 immune checkpoint inhibitors.
FDA Grants Breakthrough Therapy Designation to Tecentriq, Avastin Combo for Liver Cancer
Genentech announced that the FDA has granted Breakthrough Therapy Designation to atezolizumab (Tecentriq) in combination with bevacizumab (Avastin) as a first-line treatment for patients with the most common form of liver cancer.
Keytruda Granted Priority Review for Treatment of Advanced Hepatocellular Carcinoma
Hepatocellular carcinoma is the most common type of liver cancer in adults.
Study Evaluates Rituximab for Progressive and Relapse-Remitting MS
A retrospective observational study was published in PLOS One that investigated the safety and efficacy of rituximab in patients with progressive MS (PMS) and relapsing-remitting MS (RRMS)
Case Study: CAR T Therapy Has Early Success as Acute Myeloid Leukemia Treatment
According to the case study, an acute myeloid leukemia patient has remained cancer free for 9 months following treatment with the chimeric antigen receptor (CAR) T-cell treatment, CYAD-01, and a bone marrow transplant.
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