Raymond DeMatteo, PharmD, BCOP

Treatment selection includes patient factors, cost, adverse effects, and drug interactions.

Treatment often involves a combination of preventive measures, topical therapies, and systemic treatments.

The drug's safety profile included significant rates of nausea, vomiting, and hematologic toxicities like neutropenia and thrombocytopenia. Although promising, brigimadlin requires careful management of adverse effects, including antiemetic and hematologic support.