CLINICAL ROLE -
How to Prevent Melanoma Before it Happens
Researchers explore potential of sunscreens with cancer-preventive properties.
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Despite High Drug Cost, Advanced Anti-HCV Targeted Therapies are Cost-Saving
Drug cost mitigated by savings in health care costs on management of conditions that may result from chronic hepatitis C virus.
Merck's Oral HCV Treatment Awaits FDA Approval
Combination of grazoprevir and elbasvir has been studied in patients with genotype 1 hepatitis C who also have end-stage renal disease and are undergoing regular hemodialysis.
C-Reactive Protein: An Emerging Biomarker for Estimating Melanoma Prognosis
Protein may potentially offer a future therapeutic target.
VEGF Inhibitor Axitinib Shows Promise in BRAF Wild-Type Metastatic Melanoma
Treatment improves overall survival.
In-Depth Analysis of Sanofi and Regeneron's Cholesterol Drug Favored by FDA Panel
By lowering LDL-C levels, alirocumab may reduce cardiovascular risk.
In Hepatitis C, Could Shorter Treatment Regimens Become the New Norm?
Shorter duration could reduce the economic impact on health care spending and make treatment more convenient.
Analyzing Infectious Complications With DMARDs: A Comparative Study
Low dose methotrexate more likely to cause infectious adverse events than higher doses of the same drug.
Gout Management: Past, Present, and Future Strategies
Research ongoing to target treatment-resistant gout.
Updated Cholesterol Guidelines Accurately Identify Cardiovascular Event Risk
The 2013 American College of Cardiology/American Heart Association guidelines for determining statin eligibility more accurately identify increased risk of cardiovascular events.
Hes1: A Genetic Target for Reversing the Pathogenesis of Osteoarthritis
Research finds a potential route for targeted therapies to inhibit development and progression.
Statins in Rheumatoid Arthritis: Evidence of a Targeted Benefit?
Lower inflammation scores found in patients with RA receiving statins.
A First-Generation Antihistamine May Have Anti-HCV Properties: What is the Clinical Impact?
Preliminary evidence suggests that the first-generation antihistamines chlorcyclizine and hydroxyzine may fight HCV infection for pennies a day.
Orkambi: A New Option for a Narrow Band of Cystic Fibrosis Patients
Review the clinical data behind the FDA's approval of the combination drug Orkambi (lumacaftor/ivacaftor) for select patients with cystic fibrosis.
Bridging Raises Bleeding Risk in Atrial Fibrillation Patients on Warfarin
A practice-changing study suggests bridging anticoagulation does more harm than good in atrial fibrillation (AF) patients treated with warfarin.
Tech-Check-Tech Programs: What Pharmacists Need to Know
Enhanced workflow models for pharmacies include expanded technician responsibilities.
In-Depth Analysis of Amgen Cholesterol Drug Favored by FDA Panel
FDA officials have recommended approval for Amgen's proposed cholesterol-lowering medication, evolocumab (Repatha).
Pharmacy technicians with special certifications are taking on expanded roles in medication delivery.
Protecting Health Care Workers from Chemotherapeutic Medication
Proposed regulations call for the use of closed-system transfer devices by health care professionals who handle hazardous drugs.
Afinitor by Novartis Pharmaceuticals, Inc
Afinitor (everolimus) is approved for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer.
New Guidelines for Thyroid Disease Screening: Perspectives for Pharmacists
The US Preventive Services Task Force recently updated its clinical guidelines on screening for thyroid dysfunction.
What to Know About "Female Viagra" Approved by FDA
The FDA has approved the first treatment for female sexual dysfunction.
Cardiovascular Polypills Flounder under FDA Regulations
Fixed-dose combination (FDC) products may be grossly underavailable for cardiovascular conditions.
Vaccine Vial Monitor Systems Critical in Polio Eradication Effort
Monitors alert health workers when a vaccine has potentially been compromised by cold chain failures.
Insulin Pens: Improving Adherence and Reducing Costs
The advantages offered by insulin pens may help improve patient adherence.
New Guidelines Lower Blood Pressure Target for Coronary Artery Disease
Here are the key points and rationale behind the lower blood pressure target.
JNC 8: The Clinical Core of the Hypertension Guidelines
The JNC 8 guidelines are based on 27 large clinical trials that are often discussed in isolation, but have never been aggregated into a single source until now.
New Cardiovascular Risk Score Has Unprecedented Accuracy Worldwide
A new cardiovascular risk estimator can accurately predict heart disease and stroke risk for anyone in the world aged 40 years or older.
USP : New Regulations to Protect Health Care Workers from Hazardous Drugs
Pharmacists need to be aware of the ways in which draft regulations developed by the United States Pharmacopeia are likely to affect the handling of potentially hazardous drugs.
Triumeq by ViiV Healthcare
The FDA approved Triumeq (abacavir, dolutegravir, and lamivudine) tablets for the treatment of HIV-1 infection in patients without the HLA-B*5701 allele.