CLINICAL ROLE -
FDA Grants Melanoma Drug Accelerated Approval
Nivolumab treats patients with unresectable or metastatic melanoma who no longer respond to other drugs.
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Added Benefit for Hepatitis C Treatment Not Proven
Data for daclatasvir not suitable to prove added benefit.
FDA Approves Ovarian Cancer Drug with BRCA Test
Olaparib treats women with advanced ovarian cancer associated with defective BRCA genes.
FDA Approves Antitumor Therapy
Lanreotide is first antitumor drug to show statistically significant progression-free survival in patients with gastrointestinal and pancreatic tumors.
Hepatitis C Not Culprit of Mental Impairment in HIV Patients
Study finds hepatitis C co-infection not related to decreased mental function.
Strategies for Protecting Pharmacists from Chemotherapeutic Medication Contamination During Compounding
The use of closed-system drug transfer devices can help protect pharmacists from potential harm from exposure to hazardous drugs, such as chemotherapeutic medications.
Novel Anticancer Agent May Have Additional Applications in Targeted Therapy
FL118 could be effective in treating late stage cancers.
Study Identifies Patients Who Should Avoid Arthritis Drug Class
Specific type of non-steroidal anti-inflammatory drugs can increase heart attack risk for some people.
Drug Combination Overcomes Chemotherapy Resistance in Triple Negative Breast Cancer
Researchers pinpoint method to reverse cancer cell resistance to chemotherapy.
Oncology Drug Expanded to Treat Non-Small Cell Lung Cancer
Ramucirumab receives third indication of 2014.
Evolving Trends in Specialty Drug Pricing
How can stakeholders save money on the skyrocketing cost of specialty drugs?
The FDA today approved a new indication for ramucirumab for the treatment of metastatic non-small cell lung cancer.
The New Wave in Cancer Treatment: Customized Nuclear Medicine
Targeted radiation may also be useful in treating other diseases.
Leukemia Treatment Receives Orphan Drug Designation
Actimab-A is an alpha radiolabeled antibody in development for newly diagnosed acute myeloid leukemia patients over the age of 60.
Experimental Drug Limits Growth of Prostate Cancer
Agent found to stop growth and spread of prostate cancer with a common chromosomal abnormality.
Prostate Cancer Treatment Decreases Survival in Men with Longer Life Expectancy
Primary ADT associated with decreased survival in localized prostate cancer patients.
New Treatment Targets Most Aggressive Forms of Leukemia
Active substance overcomes treatment resistance in Philadelphia chromosome-positive leukemia.
Study: Prostate Cancer Risk Not Increased by Testosterone Therapy
Concerns still remain, however, and there is a lack of long-term data.
Current Drug Adherence Improvement Methods Ineffective
Study finds a number of measures must be taken to consistently improve medication adherence.
Psoriatic Arthritis, Rheumatoid Arthritis Carry Increased Risk of Cardiovascular Death
More severe psoriasis associated with clinically significant cardiovascular risk.
Patients Ineligible for First-Line HIV Drug Have Other Effective Options
Study finds that HIV drug regimens that exclude efavirenz are as effective as first-line antiretroviral treatment.
Muscle Relaxer May Help Treat Rare Form of Diabetes
Dantrolene found to help prevent the destruction of insulin-producing beta cells in patients with Wolfram syndrome.
Researchers Target Novel Vaccine for Approach for Brain Tumors
Study examines cellular and molecular mechanisms behind experimental vaccine.
Blood Clot Preventive Drugs Found to Protect Organs During Transplant
Protective strategy may keep organs safe and functioning optimally after the procedure.
Body Mass Index Linked to Rheumatoid Arthritis Remission
Patients significantly overweight or underweight less likely to remain in remission.
Early Lung Cancer Treatment Affected by Race, Insurance Status
Study finds African Americans and Hispanics significantly less likely to be treated with radiation.
Anti-HIV Drugs May Cause Long Term Damage to Fetal Heart Development
Study finds treatment that prevents transmission of virus from mother to child leads to reduced heart performance.
Vitamin D Deficiency Increases With Severity of Inflammatory Bowel Disease
Study finds few patients were adherent to supplements.
Orphan Drug Status Granted to Hemolytic Uremic Syndrome Treatment
The FDA has granted orphan drug designation to a treatment for a rare disease that primarily affects kidney function.