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|Articles|November 23, 2021
Pharmacy Clinical Pearl of the Day: Down Syndrome
Author(s)Saro Arakelians, PharmD
Down syndrome is the most common genetic chromosomal disorder and cause of learning disabilities in children.
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Clinical Pearl of the Day: Down Syndrome
Down syndrome is a genetic disorder caused when abnormal cell division results in an extra full or partial copy of chromosome 21.
Insight:
- Down syndrome varies in severity among individuals, causing lifelong intellectual disability and developmental delays.
- It's the most common genetic chromosomal disorder and cause of learning disabilities in children.
- Symptoms include flattened face, small head, short neck, protruding tongue, upward slanting eye lids, poor muscle tone, excessive flexibility, and short height.
- Causes might be Trisomy 21, Mosaic Down syndrome and Translocation Down syndrome.
- Early detection of the disorder will help the family take action faster and consult many providers, such as endocrinology, cardiology, neurology, speech, and physical therapy.
Sources:
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