Pharmacy Clinical Pearl of the Day: Crohn Disease

Crohn disease causes inflammation of the digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition.

Clinical Pearl of the Day: Crohn Disease

Crohn disease is a type of inflammatory bowel disease.

Explanation

  • Crohn disease causes inflammation of the digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition.
  • Symptoms include diarrhea, fever, fatigue, abdominal pain, cramping, blood in the stool, mouth sores, reduced appetite, and weight loss.
  • The condition could be genetic or caused by an immune system reaction.
  • Risk factors include age, ethnicity, family history, cigarette smoking, and non-steroidal anti-inflammatory drugs.
  • Treatment includes anti-inflammatory drugs, such as corticosteroids and oral 5-aminosalicylates; immune system suppressors such as azathioprine and methotrexate; biologics such as Remicade, Tysarbi and Stelara; antibiotics such as Cipro and Flagyl; and anti-diarrheal medications, pain relievers, vitamins, and nutrition therapy.

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