Clinical Pearl of the Day: Crohn Disease
Crohn disease is a type of inflammatory bowel disease.
- Crohn disease causes inflammation of the digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition.
- Symptoms include diarrhea, fever, fatigue, abdominal pain, cramping, blood in the stool, mouth sores, reduced appetite, and weight loss.
- The condition could be genetic or caused by an immune system reaction.
- Risk factors include age, ethnicity, family history, cigarette smoking, and non-steroidal anti-inflammatory drugs.
- Treatment includes anti-inflammatory drugs, such as corticosteroids and oral 5-aminosalicylates; immune system suppressors such as azathioprine and methotrexate; biologics such as Remicade, Tysarbi and Stelara; antibiotics such as Cipro and Flagyl; and anti-diarrheal medications, pain relievers, vitamins, and nutrition therapy.