• News
  • Media
  • Conferences
  • Publications
  • Events
  • CE
  • Resources
  • Subscribe
|Articles|December 15, 2021

Daily Medication Pearl: Ondansetron Hydrochloride (Zofran)

Zofran aids in the prevention of nausea and vomiting.

Medication Pearl of the Day: Ondansetron Hydrochloride (Zofran)

Indication: Zofran is a 5-HT3 receptor antagonist indicated for the prevention of nausea and vomiting.

Insight:

  • Dosing: Take 1 tablet every day or as needed prescribed by the provider.
  • Dosage forms: Tablets 4 mg and 8 mg (orally disintegrating tablets available), oral solution 4 mg/5 mL.
  • Adverse events (AEs): The most common AEs in adults are headache, malaise/fatigue, constipation, and diarrhea.
  • Mechanism of action: Ondansetron is a selective 5-HT3 receptor antagonist.
  • Manufacturer: GSK

Sources:

ZOFRAN (ondansetron hydrochloride) Label (fda.gov)

zofran image - Google Search

Newsletter

Stay informed on drug updates, treatment guidelines, and pharmacy practice trends—subscribe to Pharmacy Times for weekly clinical insights.

Subscribe Now!

Related Content

Latest CME

Empowering Patients With COPD: The Pharmacist's Role in Personalized Treatment Strategies
On-Demand Webinar

Empowering Patients With COPD: The Pharmacist's Role in Personalized Treatment Strategies

1.0 Credit / Pulmonology/Respiratory

View more
2025 SABCS Abstracts to Action: From Data to Decisions in HR+ Breast Cancer Care
Panel Discussion Registration

2025 SABCS Abstracts to Action: From Data to Decisions in HR+ Breast Cancer Care

February 23, 2026 | 7:00 PM ET

View more
Implementing Updated RSV Vaccination Recommendations for Older Adults: Considerations for the Pharmacist (Pharmacy Technician Credit)
On-Demand Webinar

Implementing Updated RSV Vaccination Recommendations for Older Adults: Considerations for the Pharmacist (Pharmacy Technician Credit)

0.5 Credit / Immunology

View more
Implementing Updated RSV Vaccination Recommendations for Older Adults: Considerations for the Pharmacist (Part 3)
On-Demand Webinar

Implementing Updated RSV Vaccination Recommendations for Older Adults: Considerations for the Pharmacist (Part 3)

0.5 Credit / Immunization

View more
Implementing Updated RSV Vaccination Recommendations for Older Adults: RSV Case Discussion (Pharmacy Technician Credit)
Case Conversation

Implementing Updated RSV Vaccination Recommendations for Older Adults: RSV Case Discussion (Pharmacy Technician Credit)

0.75 Credit / Immunization

View more
Advancing AML Care: Equipping Pharmacists to Implement Menin Inhibitor Therapies with Precision
Webinar Registration

Advancing AML Care: Equipping Pharmacists to Implement Menin Inhibitor Therapies with Precision

Thursday, March 5, 2026 | 12:00 PM & 7:00 PM ET

View more
Navigating Diabetes: A Guide to Effective Oral Treatments
Online Article

Navigating Diabetes: A Guide to Effective Oral Treatments

1.0 Credits / Endocrinology, Diabetes & Metabolism

View more
Advancing Acute Pain Care: Breakthrough Non-Opioid Therapies and the Pharmacist's Critical Role
On-Demand Virtual Symposium

Advancing Acute Pain Care: Breakthrough Non-Opioid Therapies and the Pharmacist's Critical Role

1.5 Credits / Pain Management/Opioids

View more
APhA 2026
In-Person + Virtual Event

APhA 2026

March 28-29, 2026

View more
Implementing Updated RSV Vaccination Recommendations for Older Adults: Incorporating ACIP Guidelines (Part 2)
On-Demand Webinar

Implementing Updated RSV Vaccination Recommendations for Older Adults: Incorporating ACIP Guidelines (Part 2)

0.5 Credit / Immunization

View more
Exploring HIV Long-Acting Injectable Uptake: How Pharmacists Can Encourage Long-Acting Injectables to Stem the Spread of HIV
On-Demand Virtual Symposium

Exploring HIV Long-Acting Injectable Uptake: How Pharmacists Can Encourage Long-Acting Injectables to Stem the Spread of HIV

1.5 Credits / HIV/AIDS, Infectious Disease

View more
Optimizing LDL-C Lowering and Adherence to Hyperlipidemia Guidelines
On-Demand Webinar

Optimizing LDL-C Lowering and Adherence to Hyperlipidemia Guidelines

1.0 Credit / Cardiology

View more
Revolutionizing Acute Pain Relief: Emerging Nonopioid Therapies and the Essential Role of Managed Care
AJMC Supplement

Revolutionizing Acute Pain Relief: Emerging Nonopioid Therapies and the Essential Role of Managed Care

2.0 Credits / Pain Management

View more
Innovations in Medicine: 2024 Lineup of New and Approved Specialty Drugs (Pharmacy Technician Credit)
Online Article

Innovations in Medicine: 2024 Lineup of New and Approved Specialty Drugs (Pharmacy Technician Credit)

2.0 Credits / General Pharmacy

View more
Understanding the Pearls and Pitfalls of Nimodipine in Aneurysmal Subarachnoid Hemorrhage: Opportunities to Improve Patient Outcomes
Webinar Registration

Understanding the Pearls and Pitfalls of Nimodipine in Aneurysmal Subarachnoid Hemorrhage: Opportunities to Improve Patient Outcomes

February 19, 2026 | March 5, 2026 | 1:00 PM & 8:00 PM ET

View more
Implementing Updated RSV Vaccination Recommendations for Older Adults: Incorporating ACIP Guidelines (Pharmacy Technician Credit)
On-Demand Webinar

Implementing Updated RSV Vaccination Recommendations for Older Adults: Incorporating ACIP Guidelines (Pharmacy Technician Credit)

0.5 Credit / Immunization

View more
Implementing Updated RSV Vaccination Recommendations for Older Adults: RSV Case Discussion
Case Conversation

Implementing Updated RSV Vaccination Recommendations for Older Adults: RSV Case Discussion

0.75 Credit / Immunization

View more
Implementing Updated RSV Vaccination Recommendations for Older Adults: Introduction and Disease Burden (Part 1)
On-Demand Webinar

Implementing Updated RSV Vaccination Recommendations for Older Adults: Introduction and Disease Burden (Part 1)

0.5 Credit / Immunization

View more
Innovations in Medicine: 2024 Lineup of New and Approved Specialty Drugs
Online Article

Innovations in Medicine: 2024 Lineup of New and Approved Specialty Drugs

2.0 Credits / General Pharmacy

View more
Implementing Updated RSV Vaccination Recommendations for Older Adults: Introduction and Disease Burden (Pharmacy Technician Credit)
On-Demand Webinar

Implementing Updated RSV Vaccination Recommendations for Older Adults: Introduction and Disease Burden (Pharmacy Technician Credit)

0.5 Credit / Immunization

View more
Hyperlipidemia Overview and the Clinical and Economic Burden
On-Demand Webinar

Hyperlipidemia Overview and the Clinical and Economic Burden

1.0 Credit / Cardiology

View more
Best Practices for Management of Hyperlipidemia: A Focus on Guidelines and Patient Adherence
Podcast

Best Practices for Management of Hyperlipidemia: A Focus on Guidelines and Patient Adherence

0.5 Credit / Cardiology

View more