Daily Medication Pearl: Glatiramer Acetate Injection (Copaxone) for Multiple Sclerosis

Glatiramer acetate modifies immune processes that are believed to be responsible for the pathogenesis of multiple sclerosis.

Medication Pearl of the Day: Glatiramer acetate injection (Copaxone)

Glatiramer acetate is indicated for the treatment of relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

Explanations:

  • Dosage: For subcutaneous injection only; doses are not interchangeable
    • Glatiramer acetate 20 mg/ml per day
    • Glatiramer acetate 40 mg/mL 3 times per week
  • Dosage forms: Injection of 20 mg/mL in a single-dose, prefilled syringe with a white plunger. Injection of 40 mg/mL in a single-dose, prefilled syringe with a blue plunger.
  • Adverse events: Injection site reactions, vasodilatation, rash, dyspnea, and chest pain.
  • Mechanism of action: Glatiramer acetate is thought to act by modifying immune processes that are believed to be responsible for the pathogenesis of MS.
  • Manufacturer: Teva

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