Medication Pearl of the Day: Glatiramer acetate injection (Copaxone)
Glatiramer acetate is indicated for the treatment of relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
- Dosage: For subcutaneous injection only; doses are not interchangeable
- Glatiramer acetate 20 mg/ml per day
- Glatiramer acetate 40 mg/mL 3 times per week
- Dosage forms: Injection of 20 mg/mL in a single-dose, prefilled syringe with a white plunger. Injection of 40 mg/mL in a single-dose, prefilled syringe with a blue plunger.
- Adverse events: Injection site reactions, vasodilatation, rash, dyspnea, and chest pain.
- Mechanism of action: Glatiramer acetate is thought to act by modifying immune processes that are believed to be responsible for the pathogenesis of MS.
- Manufacturer: Teva