Medication Pearl of the Day: Avapro (Irbesartan)
Indication: Avapro (Irbesartan)is an angiotensin II receptor blocker indicated for the treatment of hypertension and used to lower blood pressure.
- Dosing: Avapro (Irbesartan) can be taken at 150 to 300 mg daily.
- Dosage forms: Avapro (Irbesartan) comes in tablet forms at 75 mg, 150 mg, and 300 mg.
- Adverse events (AEs): In type 2 diabetic patients, the most common AE experienced by patients on Avapro (Irbesartan) is nephropathy, or the deterioration of kidney function. The AEs that were found to be more frequent than placebo were hyperkalemia dizziness, orthostatic dizziness, and orthostatic hypotension.
- Mechanism of action: Avapro (Irbesartan) blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively binding to the angiotensin II receptor type 1 found in many tissues.
- Manufacturer: Lupin Pharma
AVAPRO (irbesartan) tablets (fda.gov)