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Opinion|Videos|August 27, 2026
cGVHD Today and Where Axatilimab Fits
Brooke Adams, PharmD, BCOP, describes the clinical reality of third-line cGVHD: patients with relapsed or refractory disease after steroids, calcineurin inhibitors, and at least 1 approved second-line agent.
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Brooke Adams, PharmD, BCOP, describes the clinical reality of third-line cGVHD: patients with relapsed or refractory disease after steroids, calcineurin inhibitors, and at least 1 approved second-line agent. She describes what hitting a ceiling looks like—escalating symptom burden, organ involvement, and functional decline—and positions axatilimab within the unmet need that prompted its development.
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