Boehringer Ingelheim and BioMed X Apply Crowdsourcing to Establish a Team of Scientists for Identifying Key Epigenetic Regulators of COPD

PRESS RELEASE

Ingelheim and Heidelberg, Germany, 21 September, 2015 — Boehringer Ingelheim and BioMed X announced today that they have successfully applied a crowdsourcing approach to establish a research team of outstanding scientists from around the world with bright ideas, who will endeavor to identify new approaches for the treatment of patients with chronic obstructive pulmonary disease (COPD).

COPD is a chronic, progressive, treatable but incurable lung disease affecting 210 million people worldwide. It is a growing world health priority and is predicted to become the 3rd leading cause of death by 2030. Boehringer Ingelheim has been a leader in the treatment of respiratory disease for over 90 years and continues to explore a pipeline of unique compounds to help patients with COPD, asthma, idiopathic pulmonary fibrosis (IPF), lung cancer and other respiratory diseases.

The interdisciplinary team will focus on the characterization of epigenetic regulators driving hallmarks of the COPD pathophysiology, as recent evidence indicates that epigenetic mechanisms could be major drivers of this devastating disease. Epigenetics is defined as heritable changes in gene expression or phenotype that do not involve a change in the underlying DNA sequence, Renata Jurkowska will head the research team that will be established in the BioMed X Innovation Center located on the campus of the University of Heidelberg, Germany.

Christian Tidona, founder and Managing Director of BioMed X explained: “the newly formed research team will build on our strong scientific networks in Heidelberg and the Biotech Cluster Rhine-Neckar. The team will be guided by experienced mentors from academia and Boehringer Ingelheim and will receive an intensive entrepreneurship and leadership training”.Michel Pairet, Senior Corporate Vice President of Research and Non-clinical Development at Boehringer Ingelheim said “we are very enthusiastic about working with this highly motivated team of talented scientists at the BioMed X Innovation Center”. He continued, “we firmly believe that crowd sourcing is an exciting and refreshing way to find unconventional solutions based on the diversity of talents and ideas. This project is ideally suited to integrate breakthrough science in epigenetics research and emerging insights into the pathophysiology of COPD. Understanding epigenetic mechanisms will allow us to discover unknown drivers of the disease and accelerate the discovery of new medicines for treating patients with COPD”.

The research team will be sponsored by Boehringer Ingelheim for two years with the option to extend the funding period up to a total of four years. Further details of the agreement are not disclosed.