Biologic Drugs Combined with Ultraviolet Phototherapy Viable in Severe Psoriasis

Article

Combination therapy may be viable for patients with moderate-to-severe psoriasis unresponsive to non-biologic treatments.

A review on the combination of biologic and narrowband ultraviolet B (NBUVB) phototherapy was found to be safe and viable for the treatment of moderate-to-severe psoriasis, in a study published by Dove Medical Press.

Researchers conducted an extensive PubMed search for studies that evaluated the safety and efficacy of this combination therapy. The results of the analysis showed that in total, 9 out of 10 studies demonstrated favorable safety and efficacy in combining biologic and phototherapy.

The findings were especially significant, because it is common for subsets of patients do not respond adequately to non-biologic therapy.

“Although no regimen involving the combination of a biologic agent and phototherapy has been approved for the management of moderate-to-severe psoriasis, combination therapy appears to be a viable clinical strategy, especially for psoriasis unresponsive to monotherapy,” said lead study author Benjamin Farahnik. “NBUVB in combination with biologics appears to be especially effective.

“Skillfully combining biologic agents with non-biologic treatments broadens the armamentum for the long-term control of psoriasis without much increase in risks. Nevertheless, further studies are required to assess the long-term safety and efficacy of such combinations.”

Related Videos
male pharmacist using digital tablet during inventory in pharmacy | Image Credit: sofiko14 - stock.adobe.com
Pharmacist holding medicine box in pharmacy drugstore. | Image Credit: I Viewfinder - stock.adobe.com
Pharmacy Drugstore Checkout Cashier Counter | Image Credit: Gorodenkoff - stock.adobe.com
Medicine tablets on counting tray with counting spatula at pharmacy | Image Credit: sutlafk - stock.adobe.com
Capsules medicine and white medicine bottles on table | Image Credit: Satawat - stock.adobe.com
Human cell or Embryonic stem cell microscope background | Image Credit: Anusorn - stock.adobe.com
Concept of health care, pharmaceutical business, drug prices, pharmacy, medicine and economics | Image Credit: Oleg - stock.adobe.com
Biosimilar pharmaceutical drug bottle on blue background. | Image Credit: Carl - stock.adobe.com
Pharmaceutical manufacture background with glass bottles with clear liquid on automatic conveyor line. | Image Credit: wacomka - stock.adobe.com
Bottle and scattered pills on color background, top view | Image Credit: New Africa - stock.adobe.com
© 2024 MJH Life Sciences

All rights reserved.