According to the IQVIA Institute for Human Data Sciences’ Global Use of Medicines report for 2024, the defined daily doses are expected to increase in North America by 1.3% compound annual growth rate from 2024 to 2028, with an increase of 2.3% globally.1
Previously, in a study comparing the percentage of adults with polypharmacy from 1999 to 2000 and 2017 to 2018, the rate of polypharmacy rose from 8.2% to 17.1%. Polypharmacy had a greater prevalence in elderly individuals, adults with heart disease, and adults with diabetes, according to the study published in Global Health Research and Policy.2
Further, according to an article published by Pharmacy Times, polypharmacy is commonly seen in adults aged 65 years and older who have multiple disease states and could frequent a variety of specialty providers. With a lack of continuity among providers, patients can experience duplicate medications, drug-drug interactions, drug-disease state interactions, and an increased risk of adverse events.3 Additionally, polypharmacy is especially prevalent in complex diseases, including cancer, in which individuals can receive medication to treat cancer as well as their other comorbidities. Not only can duplicate therapies be prescribed, but drug-related costs can also pose an issue, the authors of the article wrote.4
Sometimes polypharmacy is inevitable for patients, so pharmacists play an important role in supplying information to patients about their medications. However, traditional models of education such as printed handouts can be easily discarded or misplaced, causing patients to lose access to this information. Consequently, they could struggle with adherence or face a higher safety risk due to their medications, especially as usage continues to grow, according to a press release from EnlivenHealth.5