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The Pharmacist Journey With Aimovig® (erenumab-aooe)


Aimovig® is indicated for the preventive treatment of migraine in adults.

Important Safety Information

Contraindication: Aimovig® is contraindicated in patients with serious hypersensitivity to erenumab-aooe or to any of the excipients. Reactions have included anaphylaxis and angioedema.

Hypersensitivity Reactions: Hypersensitivity reactions, including rash, angioedema, and anaphylaxis, have been reported with Aimovig® in post marketing experience. Most reactions were not serious and occurred within hours of administration, although some occurred more than one week after administration. If a serious or severe reaction occurs, discontinue Aimovig® and initiate appropriate therapy.

Constipation with Serious Complications: Constipation with serious complications has been reported following the use of Aimovig® in the postmarketing setting. There were cases that required hospitalization, including cases where surgery was necessary. The onset of constipation was reported after the first dose in a majority of these cases, but patients also reported later on in treatment. Aimovig® was discontinued in most reported cases. Constipation was one of the most common (up to 3%) adverse reactions reported in clinical studies.

Monitor patients treated with Aimovig® for severe constipation and manage as clinically appropriate. Concurrent use of medications associated with decreased gastrointestinal motility may increase the risk for more severe constipation and the potential for constipation-related complications.

Hypertension: Development of hypertension and worsening of pre-existing hypertension have been reported following the use of Aimovig® in the postmarketing setting. Many of the patients had pre-existing hypertension or risk factors for hypertension. There were cases requiring pharmacological treatment and, in some cases, hospitalization. Hypertension may occur at any time during treatment but was most frequently reported within seven days of dose administration. In the majority of the cases, the onset or worsening of hypertension was reported after the first dose. Aimovig® was discontinued in many of the reported cases.

Monitor patients treated with Aimovig® for new-onset hypertension, or worsening of pre-existing hypertension, and consider whether discontinuation of Aimovig® is warranted if evaluation fails to establish an alternative etiology.

Adverse Reactions: The most common adverse reactions in clinical studies (≥ 3% of Aimovig®-treated patients and more often than placebo) were injection site reactions and constipation.

Please see Aimovig® full Prescribing Information


Mark Percifield, PharmD, will provide community pharmacists with key information about Aimovig® to support patient education along their treatment journey in this webcast, "The Pharmacist Journey With Aimovig®":

  • The presentation objectives are to: Understand the clinical burden of migraine, diagnostic criteria, and developments in acute and preventive migraine treatment
  • Take a closer look at Aimovig®, which is indicated for the preventive treatment of migraine in adults, highlighting its mechanism of action, efficacy and safety data from clinical studies
  • Discuss a hypothetical case study and emphasize the role of the community pharmacist in helping patients start and stay on treatment with Aimovig®, as prescribed
  • Review Aimovig® dosing, administration, and storage information and available resources that can be used during counseling
  • Explore Aimovig Ally product support and access resources available along the post-prescription journey, including patient enrollment and step-by-step guidance on how to process the Aimovig Ally Access Card


Mark Percifield, PharmD

Mark Percifield, PharmD, is a Specialty Pharmacy Manager in Largo, FL, for the past 11 years. Dr. Percifield attended the University of Florida in Gainesville, FL, where he graduated with High Honors and earned his Doctor of Pharmacy degree. Dr. Percifield has more than 20 years of experience in pharmaceutical management. He has previously served as Clinical Assistant Professor at the University of Florida and West Virginia University. Dr. Percifield has been published in the St. Petersburg Times regarding the promotion of electronic prescriptions for patient safety.

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