February 2010

Review of Outcomes Associated With Formulary Restrictions: Focus on Step Therapy

April 06, 2010

The American Journal of Pharmacy Benefits

As healthcare spending continues to rise, more employers, managed care organizations, and pharmacy benefit managers are implementing novel pharmacy benefit designs and formulary management policies to control drug spending.

Initiating Drug Therapy in Multiple Sclerosis Patients: Effect on Healthcare Costs

April 06, 2010

The American Journal of Pharmacy Benefits

Multiple sclerosis (MS) is a disease of inflammatory demyelination of axons of the central nervous system that results in episodes of transient neurologic deficits, progressing to permanent neurologic deterioration over time.1 The cause of MS remains unclear, but it is thought to involve both genetic susceptibility and environmental triggers, possibly viral, which result in self-sustaining autoimmune dysfunction.

Clearing the Pathway for Molecular Diagnostic Tests

April 06, 2010

The American Journal of Pharmacy Benefits

People living with chronic conditions benefit from many medical advances developed over the past 20 years. Many diseases that were once fatal diagnoses are now managed utilizing various drug therapies. However, far too often, treatments may work well for some people, while providing marginal benefits or causing significant harm to others.

Staging Colon Cancer: New Directions and Managed Care Implications

April 06, 2010

The American Journal of Pharmacy Benefits

In September 2009, the Pharmacy & Therapeutics Society gathered a study group of 12 managed care medical and pharmacy directors. The objective was to examine the impact that biomarker-based assays could have on the approaches payers and providers use to manage cancer.

Report on the 9th Annual Conference of The Pharmacy & Therapeutics Society

April 06, 2010

The American Journal of Pharmacy Benefits

Rising healthcare costs, lack of standardized practice and variation in practice by geographic area (including failure to follow clinical guidelines), patient nonadherence, and continued perceptions of poor value for the money that is spent continue to plague healthcare performance, according to Joshua S. Benner, PharmD, ScD, Engelberg Center for Health Care Reform, The Brookings Institution.

Opportunity and Challenges in Treating Neurologic Conditions

April 06, 2010

The American Journal of Pharmacy Benefits

This issue of The American Journal of Pharmacy Benefts includes several articles about neurologic conditions and the medications used to treat them. We chose to focus on this area for 2 reasons.

Drug Utilization Patterns in Patients With Alzheimer's Disease

April 06, 2010

The American Journal of Pharmacy Benefits

The proportion of Americans diagnosed with Alzheimer's disease (AD) is projected to increase almost 2-fold over the next couple of decades due to size of the Baby Boom generation compared with the total US population.