EP. 1: Early Challenges in the cGVHD Journey
Panelists discuss how early diagnosis, evolving treatment strategies, and pharmacist-led interventions are advancing chronic graft-vs-host disease (cGVHD) management by addressing unmet needs, improving care coordination, and enhancing patient access to emerging therapies.
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EP. 2: Navigating the Path to Second-Line Therapy
Panelists discuss how second-line therapy selection and individualized care strategies are essential in chronic graft-vs-host disease (cGVHD) management, emphasizing the need to reduce steroid-related toxicity, address patient-specific factors, and leverage pharmacist expertise to optimize outcomes.
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EP. 3: Steroid-Refractory cGVHD: A Look at FDA-Approved Options
Panelists discuss how recent FDA approvals and evolving evidence for second-line treatments, including ruxolitinib, ibrutinib, and belumosudil, are reshaping chronic graft-vs-host disease (cGVHD) management by offering tailored, evidence-based options for steroid-refractory patients.
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EP. 4: Emerging Data: Impacts of ROCKstar and AGAVE-201
Panelists discuss how factors such as patient preferences, disease severity, organ-specific involvement, and adverse effect profiles influence the selection of second-line therapies for steroid-refractory chronic graft-vs-host disease (cGVHD) in the context of multiple FDA-approved agents.
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EP. 5: Tailoring Therapy: Weighing Evidence, Organ Involvement, and Route of Administration
Panelists discuss how factors such as patient preferences, disease severity, organ-specific involvement, and adverse effect profiles influence the selection of second-line therapies for steroid-refractory chronic graft-vs-host disease (cGVHD) in the context of multiple FDA-approved agents.
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EP. 6: Sequencing Strategies and the Role of Combination Therapy
Panelists discuss how evolving treatment pathways at Emory Healthcare, including earlier use of emerging therapies and off-label combination treatments, are shaping the management of chronic graft-vs-host disease (cGVHD), with an emphasis on personalizing therapy based on real-world data and patient-specific factors.
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EP. 7: Pharmacist-Led Interventions for Adherence and Optimization
Panelists discuss how pharmacists improve patient outcomes in chronic graft-vs-host disease (cGVHD) by addressing accessibility and tolerability challenges, optimizing drug regimens, managing adherence, and fostering trust with patients to ensure consistent therapy and long-term success.
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EP. 8: Overcoming Barriers to Access and Treatment
Panelists discuss how pharmacists are essential in managing chronic graft-vs-host disease (cGVHD) by addressing challenges like toxicity, financial and logistical barriers, and a lack of awareness, while advocating for patient education, collaboration with health care teams, and ensuring access to necessary therapies.
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EP. 9: Multidisciplinary Collaboration in cGVHD Care
Panelists discuss how collaboration between pharmacists and health care providers is essential for optimizing treatment outcomes in chronic graft-vs-host disease (cGVHD), emphasizing the importance of education, symptom management, and a multidisciplinary approach to ensure comprehensive, patient-tailored care.
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EP. 10: Looking Ahead: Research Priorities and Final Insights
Panelists discuss how advancing chronic graft-vs-host disease (cGVHD) management involves improving steroid response rates, exploring combination therapies, utilizing biomarkers for personalized treatment, and striving for steroid-free first-line options to enhance patient outcomes and reduce long-term adverse effects.
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