Ashley Gallagher, Editor

Improvement in recurrence-free survival was seen primarily in individuals with very high-risk renal cell carcinoma, whereas individuals with intermediate high-risk disease showed no improvements in survival.

The median overall survival was 66 months for individuals with hormone receptor-positive/human epidermal growth factor receptor-negative advanced or metastatic breast cancer administered at least 1 dose reduction of ribociclib (Kisqali) from the starting dose of 600 mg.

The gout medicine is a potential treatment option for individuals hospitalized for the cardiovascular condition, analysis suggests.

The findings show that at 90 days, the modified Rankin Score (mRS) had a significantly greater number of individuals with an improvement of 2 points or greater.

Company releases data at the American Society of Clinical Oncology Annual Meeting 2022 showing that the drug is well-tolerated in patients with solid tumors.

Analysis also shows a reduction in the need for opiate painkillers, and there was a decrease in other cancer-related symptoms, according to results published in Frontiers in Pain Research.

The medications are linked with reduced negative emotional bias, according to new research published in Biological Psychiatry.

Analysis provides new understanding of the effect of probiotics on the tiniest of infants in the neonatal intensive care.

In ECOSPOR III, the lead therapeutic candidate incorporated itself durably and rapidly into the microbiome to prevent recurrence, the company says.

The FreeStyle Libre 3 is the most accurate 14-day continuous glucose monitor with a 7.9% overall mean absolute relative difference and readings are sent directly to a smartphone every minute.

Further sensitivity analyses to control for family alcohol consumption, family history, liver disease, and smoking, finds no convincing evidence that these factors affected the results.

Research suggests that individuals receiving a vaccine, such as ones from AstraZeneca and Johnson & Johnson, were more vulnerable to infection by new variants.

Taking multiple prescription drugs and supplements can be especially dangerous for individuals with cancer who are about to undergo therapy.

When both the clinical criteria and genetic testing were combined, 6.6 familial hypercholesterolemia cases per 1000 individuals screened were found.

Using machine learning, they find patterns in electronic health record data to help ascertain which individuals likely have the condition.

Investigators establish 2 predictive models, which had excellent performance, and included 90 children.

The approval is supported by data from a global phase 3 trial assessing the use of the drug for individuals with previously untreated IDH1-mutated acute myeloid leukemia.

The study results support a hypothesis for a differentiated mechanism from risankizumab, the company says.

Investigators suggested a new test method for the infection with ESAT6/CFP10 and to monitor the disease development and treatment with Ag85B.

But HRT is associated with positive changes to cholesterol levels, though the sample size was small, the analysis shows.

The analysis, results of which are published in The Lancer Psychiatry, also identifies genetic markers that seem to influence how quickly the body eliminates the medication from its system.

Study results also show a 50% increase in the precancerous condition, Barrett esophagus, between 2012 and 2019, in the same population.

Analysis finds that reported adverse events rarely led to the discontinuation of therapy when used as a migraine prophylaxis.

Latest results of the phase 3 IKEMA trial demonstrate the longest median progression-free survival on a proteasome inhibitor backbone in this population, Sanofi says.

The study marks the first time an albuterol/budesonide fixed-dose combination rescue medication has reduced severe exacerbations, the company said.

Independent committee recommends the phase 3 clinical trial continues to assess other primary and secondary endpoints for the treatment of unresectable or metastatic urothelial carcinoma.

Goal of modernizing therapeutic equivalence rating determination act is to increase availability, competition, drive down prescription costs.

Physicians often overlook those with lower BMIs who have nonalcoholic fatty liver disease and lower rates of other comorbidities, investigators say.

Analysis shows the activity of a specific enzyme, Butyrylcholinesterase, was significantly lower in those who subsequently died of sudden infant death syndrome.

Infections at community hospitals fell by 63% after 1 year and 77% after 3 years, new data show.