Levonorgestrel and ethinyl estradiol 0.15 mg/0.03 mg is indicated to prevent pregnancy in women who choose to use combination oral contraceptives. These combination progestin and estrogen tablets represent Mylan’s tenth oral contraceptive product launch in the United States.

The use of oral contraceptives is associated with increased risk of thromboembolic disorders and vascular issues, though the most common side effects are nausea, vomiting, unusual bleeding, and a change in menstrual flow.

Since cigarette smoking can increase the risk of cardiovascular side effects from oral contraceptive use, Mylan advised those taking levonorgestrel and ethinyl estradiol tablets to not smoke.

Seasonale had US sales of approximately $57.3 million in 2014, according to IMS Health.