Daily Medication Pearl: Tapinarof (Vtama)

Tapinarof (Vtama) cream, 1% is an aryl hydrocarbon receptor agonist indicated for the topical treatment of plaque psoriasis in adults.

Medication Pearl of the Day: Tapinarof (Vtama)

Indication: Tapinarof (Vtama) cream, 1% is an aryl hydrocarbon receptor agonist indicated for the topical treatment of plaque psoriasis in adults.

Insight:

  • Dosing: Apply a thin layer of tapinarof cream to affected areas once daily.
  • Dosage forms: Cream, 1%- each gram of tapinarof cream contains 10 mg of tapinarof.
  • Adverse events: Most common adverse reactions (incidence ≥ 1%) in patients treated with tapinarof cream were folliculitis, nasopharyngitis, contact dermatitis, headache, pruritus, and influenza.
  • Mechanism of action: Tapinarof is an aryl hydrocarbon receptor agonist. The specific mechanisms by which tapinarof cream exerts its therapeutic action in psoriasis patients are unknown.

Source: https://www.vtama.com/hcp/PI/