Daily Medication Pearl: Dronabinol (Marinol)


Marinol is a cannabinoid indicated for anorexia associated with weight loss in patients with AIDS.

Medication Pearl of the Day: Dronabinol (Marinol)

Indication: Marinol is a cannabinoid indicated in adults for the treatment of anorexia associated with weight loss in patients with AIDS.


  • Dosing: The recommended adult starting dosage is 2.5 mg orally twice daily, 1 hour before lunch and dinner.
  • Dosage forms: Capsules: 2.5 mg, 5 mg, 10 mg.
  • Adverse events (AEs): Most common AEs are abdominal pain, dizziness, euphoria, nausea, paranoid reaction, somnolence, thinking abnormal, and vomiting.
  • Mechanism of action: Dronabinol is an orally active cannabinoid, which has complex effects on the central nervous system, including central sympathomimetic activity
  • Manufacturer: AbbVie


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