Medication Pearl of the Day: Dronabinol (Marinol)
Indication: Marinol is a cannabinoid indicated in adults for the treatment of anorexia associated with weight loss in patients with AIDS.
- Dosing: The recommended adult starting dosage is 2.5 mg orally twice daily, 1 hour before lunch and dinner.
- Dosage forms: Capsules: 2.5 mg, 5 mg, 10 mg.
- Adverse events (AEs): Most common AEs are abdominal pain, dizziness, euphoria, nausea, paranoid reaction, somnolence, thinking abnormal, and vomiting.
- Mechanism of action: Dronabinol is an orally active cannabinoid, which has complex effects on the central nervous system, including central sympathomimetic activity
- Manufacturer: AbbVie