News|Articles|September 11, 2026

AI Model Could Help Address Missing ECOG Performance Status in Real-World Oncology Data

Author(s)Ryu Kariyawasam-Chavez, Content Associate

Carole R. Berini, PhD, and Saamir Pasha, MPH, of Ontada discuss a model designed to estimate missing baseline ECOG performance status in advanced prostate cancer and the validation needed before it can support broader real-world evidence research.

ECOG performance status helps clinicians assess a patient’s ability to perform daily activities and can inform treatment selection and prognosis. However, the measure is often missing at the specific time points needed for real-world evidence studies, potentially limiting sample sizes and introducing selection bias.