Higher Vitamin D Level May Improve Parkinson’s Disease Symptoms

Published Online: Monday, March 17, 2014
Follow Pharmacy_Times:
The results of a new study found that higher levels of vitamin D were associated with improved cognition and mood in patients with PD.

The study, published in the December 2013 issue of the Journal of Parkinson’s Disease, examined neuropsychiatric function and serum 25-hydroxyvitamin D levels in 286 PD patients with and without dementia. The researchers measured global cognitive function, verbal memory, fluency, function, executive function, disease severity, and depression for each patient, comparing these scores with each patient’s vitamin D level.

The results indicated that higher vitamin D levels were associated with better performance on many neuropsychiatric tests in patients without dementia. Significant relationships were found between vitamin D levels and verbal fluency and verbal memory. Higher vitamin D levels tended to decrease the risk of depression in patients without dementia.

Although the results of the study suggest a relationship between vitamin D levels and improved mood and cognitive function in patients with PD, they do not prove causation, the authors of the study note. Patients with more advanced forms of the disease may get less sun exposure due to their limited mobility, causing the lower levels of vitamin D.

Related Articles
The media has been quick to discuss research findings on vitamin D supplementation’s potential role in combating osteoporosis, correcting deficiency in chronic kidney disease, improving heart health, and extending life, which raises the question of whether patients should be screened routinely for vitamin D deficiency.
Vitamin D supplements can reduce the severity and duration of chronic obstructive pulmonary disease flare-ups by more than 40%.
Vitamin D may have a regulative role in seasonal affective disorder development.
Vitamin D deficiencies are causally associated with increased mortality rates.
Latest Issues
$auto_registration$