Novartis announced that it has submitted New Drug Applications to the FDA for QVA149 and NVA237, investigational drugs for the long-term maintenance treatment of chronic obstructive pulmonary disease, following positive results from phase 3 trials of the drugs.
Rhinovirus infection tends to aggravate other conditions in the elderly.
Tiotropium, a once-daily inhaled long-acting anticholinergic bronchodilator, provides airflow improvement for at least 24 hours in chronic obstructive pulmonary disease patients. Its use has been linked to fewer exacerbations, less dyspnea, and improved quality of life.
Patients with bronchial asthma or chronic obstructive pulmonary disease fare best with metered dose inhalers that have spacer devices.