Dramatically Reduced Testosterone Levels Found in Young Obese Males

Published Online: Thursday, December 13, 2012
Follow Pharmacy_Times:
Obese young males appear to have 40% to 50% less testosterone than their normal-weight peers, according to the results of a small study published online on September 13, 2012, in Clinical Endocrinology. The study was carried out by a team of researchers at the State University of New York at Buffalo who previously established an association between low testosterone levels and obesity in adult men.

The researchers tested morning fasting blood samples from 25 obese and 25 normal-weight males aged 14 to 20 years who were pubertal or post-pubertal. Their results showed that, after controlling for age and stage of sexual development, obese participants had significantly lower total testosterone (10.5 vs 21.44 nmol/L), free testosterone (0.22 vs 0.39 nmol/L), and calculated free testosterone (0.26 vs 0.44 nmol/L) than normal-weight participants.

The results need to be confirmed with a larger number of participants, but they are noteworthy because the reduced testosterone levels increase the potential of impotence and infertility in adulthood. “These findings demonstrate that the effect of obesity is powerful, even in the young, and that lifestyle and nutritional intake starting in childhood have major repercussions throughout all stages of life,” said Paresh Dandona, MD, PhD, the study’s lead author, in a press release.

Related Articles
Children exposed to antibiotics during the second or third trimester of pregnancy have an 84% higher risk of being obese at age 7 compared with children who were not exposed to the drugs in utero, according to new research published in the Journal of Obesity.
The new Diabetes Health Coach creates a personalized experience designed to help people living with diabetes improve their diabetes management.
The AHA is proud to stand side-by-side with the people of Berkeley as they become the first city in our nation to take on a bold initiative that will provide further evidence to the effectiveness of taxing sugary drinks at a penny per ounce.
Asthmatics with vitamin D deficiency are significantly more susceptible to acute asthma attacks.
Latest Issues
$auto_registration$