Mr. Erickson is director of professional affairs at Gallipot Inc.
Loxapine suspension is not available. How can I compound the suspension for a patient?
Loxapine is an anxiolytic. Loxapine 1 mg is provided by Loxapine succinate 1.36 mg or loxapine HCl 1.12 mg. The latter is no longer available in the United States. The starting adult dose is 10 mg twice daily in psychoses and may be increased in the first 7 to 10 days of therapy; usual maintenance doses are 60 to 100 mg daily, divided into 2 to 4 doses. Absorption, distribution, and effects are nearly identical regardless of route, and first-order degradation of loxapine succinate should approximate that of loxapine HCl; therefore, it is reasonable to suggest compounding loxapine succinate suspension for oral administration.
Loxapine Succinate Oral Suspension/Solution
qs ad 100%
Beyond-Use Date: 14 days, per USP <795>
E-mail your compounding questions to .
Get to know RESPIMAT, the slow-moving mist inhaler from Boehringer Ingelheim Pharmaceuticals, Inc.
Watch the RESPIMAT video and test your knowledge with a short multiple-choice quiz. When you get all the answers right, you’ll receive a certificate naming you a RESPIMAT T.O.P. Performer. Why not check it out today?
Clinical features with downloadable PDFs