Probiotics Alleviate IBS Symptoms

NOVEMBER 01, 2005

The etiology of irritable bowel syndrome (IBS) has not been fully defined, and the effects of probiotics on this gastrointestinal (GI) motility disorder remain unclear. Kajsa Kajander, MSc, and colleagues conducted a randomized, double-blind, placebo-controlled trial to investigate the effects of a probiotic mixture containing Lactobacillus rhamnosus GG, L rhamnosus LC705, Bifidobacterium breve Bb99, and Propionibacterium freudenreichii subsp shermanii JS on IBS symptoms.

Patients meeting Rome I or Rome II criteria for IBS (n = 103) were treated with a probiotic capsule or a placebo daily for 6 months. GI symptoms and bowel habits were recorded.

At the end of the study, the median reduction in symptom score (abdominal pain + distension + flatulence + borborygmi) was 42% in the probiotic group, compared with 6% in the placebo group (P = .015). For individual symptoms, borborygmi was milder in the probiotic group (P = .008), but no significant trends were observed for other individual symptoms. These results suggested that this probiotic mixture is effective in alleviating symptoms associated with IBS (Alimentary Pharmacology and Therapeutics, September 2005).




SHARE THIS SHARE THIS
0
 

In Seniors: Consider CMV Serostatus
When Recommending Flu Vaccine

Older people who have cytomegalovirus seem to have less robust responses to the trivalent influenza vaccine than those who do not have CMV.


 

 

Conference Coverage
News from the year's biggest meetings


Pharmacist Education
Clinical features with downloadable PDFs


 

SIGN UP FOR THE PHARMACY TIMES NEWSLETTER
Personalize the information you receive by selecting targeted content and special offers.