Investigators determined that injections of the natural hormone oxyntomodulin resulted in significant weight loss in a 4-week study. The body releases this hormone after meals to make people feel less hungry. Researchers randomly injected oxyntomodulin or placebo before meals to 26 obese and overweight patients 3 times a day, 30 minutes prior to mealtime for 4 weeks. Participants maintained their normal diet and physical activity during that time. In the oxyntomodulin group, body weight decreased by 5 lb versus 1 lb in the placebo group. The group receiving the hormone injections showed changes in the levels of fat-related hormones leptin and adiponectin, which indicated a decrease in fat. The oxyntomodulin group ate less, but their perception of their meals did not change. Researchers concluded that this natural hormone "may provide a more specific treatment for obesity" than other treatments.
Ms. Farley is a freelance medical writer based in Wakefield, RI.
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
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