Insulin Resistance and Hypertension Are Linked

Published Online: Monday, August 1, 2005

Although insulin resistance is frequent in men with treated hypertension, researchers have reported that the traditional risk factors do not reliably diagnose the condition. Their study examined the rate of insulin resistance among 106 men with hypertension who were considered at high risk for cardiovascular disease and 18 healthy participants. Of the 106 patients, 21 were insulinresistant, 36 were insulin-sensitive, and 49 fell into an intermediate group. Mean blood pressure did not differ in the 3 groups.

The researchers noted that body mass index, triglyceride levels, and glucose levels were greater and high-density lipoprotein cholesterol levels were lower in the insulin-resistant group, compared with the insulin-sensitive group. Significant overlap was seen between the groups, however. In the 3 years of follow- up, 2 patients in the insulin-resistant group and 1 patient in the intermediate group were diagnosed with type 2 diabetes. The participants in the insulin-sensitive group did not develop diabetes. (The findings were reported recently in the American Journal of Hypertension.)

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