Arcoxia as Effective as Ibuprofen
Published Online: Wednesday, June 1, 2005
A study from Merck Laboratories has shown cyclooxygenase-2 (COX-2) inhibitor etoricoxib (Arcoxia) to be as effective as
ibuprofen for treating pain associated with arthritis. The 12-week
study included 528 patients being treated for arthritis of the hip
and knee and compared Arcoxia with ibuprofen and placebo.
It took about 2 weeks for Arcoxia and ibuprofen to achieve
maximum effectiveness, with symptom control lasting for another
10 weeks. Both drugs performed better than placebo and generally
were well tolerated. Arcoxia is a new COX-2 inhibitor and,
as such, has been scrutinized by the FDA along with Vioxx and
other members of that class of drugs for a possible link to heart
attack and stroke.