A study from the University of Barcelona determined that pain from menstrual cramps can be relieved significantly by ibuprofen and arginine. Dr. Camil Castelo-Branco and colleagues studied 1093 women, ranging in age from 13 to 51, who reported having menstrual cramps. Within 15 minutes of administering ibuprofen arginine, pain decreased significantly in 82% of the women. At 45 minutes, 99% of the women reported pain relief. According to researchers, the ibuprofen arginine formulation reaches peak blood concentration 20 minutes after administration. Less than 5% of the women experienced side effects, which included stomach pain and nausea. Thirty-nine percent of the women reported that their menstrual cramps interfered with daily activities such as work and school. After taking the ibuprofen arginine combination, that statistic fell to 21%. The authors concluded, "Ibuprofen arginine demonstrated a fast-acting onset of pain relief, was safe and effective in the treatment of this condition, and facilitated normal daily functions during menstruation."
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
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