A recent study
conducted at the University of Amsterdam has found that cerebral infarction is a serious concern in adults who contract community-acquired bacterial meningitis. They indicate that steps taken to prevent cerebral infarction would decrease morbidity and mortality.
Approximately 80% to 85% of all bacterial meningitis is caused by Streptococcus pneumoniae
or Neisseria meningitides;
morbidity is 30% and 10%, respectively.
Cerebrovascular complications are especially common in patients who have pneumoccal meningitis, with up to 29% affected.
These researchers looked at 696 patients, 25% of whom experienced a cerebral infarction pursuant to meningitis. They identified several factors that increase the likelihood of cerebral infarction: older age, low level of consciousness, systemic inflammation, and infection with S. pneumonia
More work is needed to determine if drug therapies can be used adjunctively to prevent cerebral infarction.