Leptin Injections May Maintain Weight Loss

FEBRUARY 01, 2006
Susan Farley

Doctors at New York Presbyterian Hospital/Columbia University Medical Center found that injecting the hormone leptin into their patients who had lost weight helped them maintain weight loss by restoring pre-weight loss levels of leptin. The researchers theorized that, after a weight loss, a person's body is leptin-deficient, which causes the weight to be gained again. They then administered leptin injections bid to 10 patients who had lost 10% to 12% of their body weight. Most of the body's changes that typically work against maintaining a reduced body weight were reversed once the levels of leptin were restored to the higher levels seen before weight loss. Lead author Michael Rosenbaum, MD, said that therapeutics that target leptin may cause physiological processes to be restored to their usual levels so that "our bodies would work with us, rather than against us, in keeping the weight off."

Ms. Farley is a freelance medical writer based in Wakefield, RI.


Become a Respimat Top Performer 

Get to know RESPIMAT, the slow-moving mist inhaler from Boehringer Ingelheim Pharmaceuticals, Inc. 

Watch the RESPIMAT video and test your knowledge with a short multiple-choice quiz. When you get all the answers right, you’ll receive a certificate naming you a RESPIMAT T.O.P. Performer. Why not check it out today? 


Pharmacy Times Strategic Alliance

Pharmacist Education
Clinical features with downloadable PDFs

Next-Generation Pharmacist® Awards

3rd Annual Convenient Healthcare and Pharmacy Collaborative Conference

Personalize the information you receive by selecting targeted content and special offers.