New Guide Provides Insight into Pharmacogenomics

Published Online: Tuesday, February 1, 2005

Lexi-Comp Inc's Pharmacogenomics Handbook is designed to inform physicians and pharmacists about the emerging science of genetic profiling in drug therapy. The reference guide offers an introduction to pharmacogenetic principles and identifies genetic factors that may influence drug disposition and/or sensitivity. The publication also identifies key polymorphisms—mutations that happen in a tiny percentage of the population—that could seriously affect drug therapies and put a patient in medical danger. An individual's DNA may have specific effects on pharmacologic activities—for example, altering drug metabolism or changing sensitivity to a drug's action at a given concentration.

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