In an effort to determine the best measure of an individual?s heart health, researchers looked at low-density lipoprotein (LDL) cholesterol (or "bad" cholesterol) and apolipoprotein B (ApoB). To investigate, the researchers looked at 1522 people in the Insulin Resistance Atherosclerosis Study. The participants went through examinations for heart disease, stroke, and diabetes risk factors. They were divided into 2 groups: 1 group would be treated based on their LDL levels, and the other group would be treated based on their ApoB levels. The findings, published recently in Circulation: Journal of the American Heart Association, included the following:
? 15% of the people who would be treated based on LDL would not be treated based on ApoB
?25% of the people who would not be treated based on LDL would be treated based on ApoB
? Overall, about 1 in 5 people
would have had a different treatment recommendation if the decision were based on ApoB
instead of LDL
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
Clinical features with downloadable PDFs