Statins May Work in Alzheimer's Disease

Published Online: Sunday, June 1, 2003

In a study of 44 patients with Alzheimer?s disease, researchers at the University of Texas Southwestern Medical Center found that statins lowered the patients? brain cholesterol levels. (Brain cholesterol contributes to the formation of amyloid plaques that damage brain cells.) During the 6-week study, participants were randomly assigned to receive either 40 mg daily of 1 of 3 different statins or 1 g daily of extended-release niacin?another kind of cholesterol-lowering drug. The results were published in the Archives of Neurology (April 21, 2003).

The researchers discovered that the 3 statin drugs reduced brain cholesterol levels by at least 20%, whereas the extended-release niacin reduced them by 10%. "This class of drugs [statins] may be potentially beneficial in the treatment of Alzheimer?s disease," said Gloria Vega, PhD, lead author of the study.

Latest Articles
Donnie Calhoun, RPh, PD, National Community Pharmacists Association (NCPA) Foundation vice president, discusses how pharmacists can prepare themselves and their business before, during, and after a disaster.
Ken Whittemore Jr, Surescript's senior vice president of professional and regulatory affairs, talks about some new transactions available that can help pharmacists.
In case you got caught up in the Thanksgiving holiday rush, here are the top trending stories you may have missed in November:
Bryan Ziegler, PharmD, executive director of Kennedy Pharmacy Innovation Center, provides some resources for community pharmacists to use when implementing new collaborative services with primary care providers.
Latest Issues