Overdosing Danger for Asthma Medication

Published Online: Saturday, February 1, 2003

An alert from the Institute for Safe Medication Practices warns of cases in which oral methotrexate was accidentally prescribed for daily instead of weekly administration. The drug is given on a daily basis for cancer treatment but is prescribed in low weekly doses for asthma, as well as rheumatoid arthritis, psoriasis, inflammatory bowel disease, and other disorders.

In order to prevent overdose, the organization suggests building alerts into electronic prescribing systems and pharmacy computers to warn clinicians whenever oral methotrexate is entered so that indication and dosing frequency can be assessed. The system also should alert pharmacists to counsel patients on proper dosing. If the purpose of the medication is not made apparent, pharmacists should speak directly with the prescriber to determine the reason for use and verify to the proper dosing schedule.

Latest Articles
This weekly video program provides our readers with an in-depth review of the latest news, product approvals, FDA rulings and more.
Chronic kidney disease incidence has grown faster than many of its common comorbidities such as diabetes and hypertension, and medications may be an underappreciated driver of this growth.
President Barack Obama’s fiscal year 2017 budget proposal calls for an additional $1.1 billion to combat the nation’s spiraling opioid epidemic.
Baxter International is voluntarily recalling intravenous solution due to leaking containers and the potential for particulate matter.
Latest Issues