Gastric Bypass Helps Control Diabetes in Moderately Obese Patients

Published Online: Friday, July 19, 2013
Follow Pharmacy_Times:
Gastric bypass surgery is usually recommended for extremely obese patients, but it may also be effective in treating type 2 diabetes, high blood pressure, and high cholesterol in moderately obese patients, according to the results of a study published in the June 5, 2013, edition of JAMA.

The study compared intensive lifestyle management interventions with Roux-en-Y gastric bypass surgery in 120 diabetes patients with BMIs between 30 and 39.9. Beginning in April 2008, all patients participated in the lifestyle intervention, and half were randomly assigned to receive Roux-en-Y gastric bypass surgery as well.

After 12 months, 49% of the participants who received gastric bypass surgery met the goals of the study, which included a glycated hemoglobin level below 7%, LDL cholesterol under 100 mg/dL, and systolic blood pressure under 130 mm Hg. By comparison, just 19% of those in the lifestyle intervention group met these goals. In addition, those in the gastric bypass group lost approximately 26% of their initial body weight compared with approximately 8% in the lifestyle intervention group. Patients who underwent gastric bypass also needed 3 fewer medications on average than those who received only lifestyle intervention.

However, more gastric bypass patients experienced nutritional deficiency, and 22 suffered serious adverse events after surgery.

Related Articles
Although there have been concerns that the human papillomavirus vaccine promotes unsafe sex among adolescents, a new study published in JAMA Internal Medicine suggests that there is no such association after all.
Medications with strong anticholinergic activity can increase the risk of developing dementia.
A recent report published in JAMA Internal Medicine confirmed a link between dementia risk and commonly used anticholinergic agents, some of which are taken regularly by older adults.
Hospitalization for pneumonia increases a patient’s risk of developing cardiovascular disease, according to a paper published in the January 20, 2015 edition of JAMA.
Latest Issues
  • photo
    Pharmacy Times
    Health-System Edition
    Directions in Pharmacy
    OTC Guide
    Generic Supplements
  • photo
    Pharmacy Careers
    Specialty Pharmacy Times