Yvette C. Terrie, BSPharm, RPh
Ms. Terrie is a clinical pharmacy writer based in Haymarket, Virginia.
According to the recommendations of
the American Dietetic Association, ideally,
healthy adults should have a daily
intake of 25 to 30 g of dietary fiber, while
children older than 2 years of age should
consume a daily intake of dietary fiber
equal to their age plus 5 g.
1 The Institute
of Medicine also recommends that individuals
should consume at least 14 g of
fiber for every 1000 calories.
2 In general,
however, the average daily intake of
fiber for most individuals in the United
States is only 14 to 15 g.
1,2
Sources of dietary fiber include fruits,
vegetables, whole grains, legumes, and
beans. The American Heart Association
(AHA) recommends that at least half
of daily grain intake come from whole
grain foods.2 Dietary fiber can be divided
into 2 basic categories: soluble and
insoluble.
- Soluble fiber slows digestion and
assists the body in absorbing vital
nutrients from foods.3,4 It dissolves
in the water found in the large intestine
and forms a gel.3,4 This form
of fiber can aid in lowering total
cholesterol levels and low-density
lipoprotein cholesterol levels, as
well as improve glycemic index in
patients with diabetes.1-3 Foods high
in soluble fiber include oat bran,
barley, peas, rice bran, beans, apple
pulp, citrus fruits, strawberries, and
psyllium husk.2,4
- Insoluble fiber does not dissolve in
water, but it increases the movement
of waste through the intestinal
tract.3,4 Insoluble fibers have
been associated with decreased
cardiovascular risks and slow progression
of cardiovascular disease,
particularly in high-risk individuals.1,2 In addition to preventing constipation,
this type of fiber may also
aid in removing toxic waste in the
colon. Foods high in insoluble fiber
include wheat bran, whole grains,
rice, flax seed, nuts, popcorn,
cabbage, beets, carrots, Brussels
sprouts, turnips, cauliflower, and
apple skin, as well as other fruits
and vegetables with skins.2,4
Adequate intake of dietary fiber is the
most recommended choice for both the
prevention and treatment of constipation
and also has an important role
in the maintenance of normal bowel
function. In addition, various studies
have demonstrated that an increased
intake of fiber can promote various
health benefits and possibly prevent
or reduce various chronic health problems.1 Examples include lowering the
risk of developing hemorrhoids or diverticulosis,
aiding in the management of
irritable bowel syndrome, promoting
better management of glucose levels
in patients with diabetes, promoting
weight loss, and restoring regularity for
individuals on low-carbohydrate diets.1-3
In addition, adequate fiber intake may
aid in lowering cholesterol levels and
blood pressure, as well as decreasing
the risk of colon cancer.1-3
Many patients still find it difficult
to consume the American Dietetic
Association's recommended intake of
dietary fiber; thus, some individuals
elect to use the various fiber products
on the market to supplement their
dietary fiber intake and to maintain
normal bowel function to prevent or
reduce episodes of constipation. Fiber
products on the market may contain
various fiber sources that include wheat
dextrin, methylcellulose, psyllium husk,
inulin, and calcium polycarbophil.
Pharmacists can provide essential guidance
to patients regarding the proper
selection of fiber supplements and can
ensure that patients use these products
correctly according to the manufacturers'
recommendations. Currently, fiber
supplements are available in a variety
of dosage formulations, such as shakes,
chewable tablets, wafers, and powders
in several different flavors (Table). Many
powder formulations can be mixed with
4 to 8 ounces of water or noncarbonated
beverage or in soft foods such as apple
sauce. Some fiber supplements contain
calcium and vitami ns/minerals. Patients
should be advised to read labels of fiber
supplements to avoid the possibility of
therapeutic duplications.
Role of the Pharmacist
When assisting patients in the selection
of fiber supplements, pharmacists
should remind patients to gradually
increase fiber intake over time to avoid
or reduce the incidence of adverse
effects, such as intestinal flatulence,
bloating, diarrhea, and cramping. The
increase should be gradual over a few
weeks, and, if possible, patients should
also increase water intake. Inadequate
fluid intake may decrease efficacy of
the product and may cause intestinal
or esophageal obstruction.5 Many manufacturers
of fiber supplements have
reminders on the product label that typically
recommend taking fiber supplements
with 8 ounces of water to avoid
choking.6-8 Patients with preexisting
medical conditions, such as those who
must restrict fluid intake (eg, patients
with renal dysfunction, congestive heart
failure)3 and those currently taking any
medications should discuss the use of
these supplements with their primary
health care provider prior to using these
products.
Furthermore, because fiber supplements
can decrease the absorption
of many medications, patients should
always be advised to take supplements
2 to 3 hours before or after other medications
and to report any concerns to
their physician. Patients should also be
reminded that the use of fiber supplements
should never be a substitute for a
fiber-rich diet that contains other essential
vitamins and minerals necessary for
health. It is important to remind patients
to try to obtain most of their daily intake
of fiber through dietary means.
Table 1 |
Examples of Available Fiber Supplements
|
|
Brand Name (Active Ingredient)
|
Manufacturer
|
|
Benefiber Products (wheat dextrin)
|
Novartis Consumer Health Inc
|
|
Benefiber Ultra Caplets
Benefiber Chewable Tablets
Benefiber Powder
Benefiber Plus Calcium (300 mg calcium)
|
|
Citrucel Products (methylcellulose)
|
GlaxoSmithKline
|
|
Citrucel Powder
Citrucel Soft Chews
Citrucel Caplets
Citrucel FiberShake
Citrucel FiberSmoothie
|
|
FiberChoice (inulin)
|
GlaxoSmithKline
|
|
FiberChoice Chewable Tablets
FiberChoice Weight Management Tablets (also contains chromium picolinate and green tea)
FiberChoice Plus Calcium (contains 500 mg calcium and 200 IU of Vitamin D)
FiberChoice Plus Multivitamins (contains 13 essential vitamins and minerals)
|
|
Fibercon Caplets (calcium polycarbophil)
|
Wyeth Consumer Healthcare
|
|
Fibersure Powder (inulin)
|
Procter & Gamble
|
|
Konsyl Products (psyllium hydrophilic mucilloid)
|
Konsyl Pharmaceuticals Inc
|
|
Konsyl-D
Konsyl Easy Mix
Konsyl Fiber Caplets (calcium polycarbophil; for individuals allergic to psyllium fiber)
Konsyl Orange
Konsyl Original
Konsyl Psyllium Capsules
Konsyl SennaPrompt
|
|
Metamucil (psyllium husk)
|
Procter & Gamble
|
|
Metamucil Original
Metamucil Fiber Powdered Drink Mixes
Metamucil Fiber Wafers
Metamucil Heart and Digestive Health Capsules
Metamucil Strong Bones (contains 300 mg calcium carbonate)
|
|
UniFiber (powdered cellulose)
|
Alaven Pharmaceuticals LLC
|
|
References
- Marlett JA, McBurney MI, Slavin JL. Position of the American Dietetic Association: health implications of dietary fiber. J Am Diet Assoc. 2002;102(7):993-1000. www.adajournal.org/article/S0002-8223(02)90228-2/fulltext.
- Fiber. American Heart Association Web site. www.americanheart.org/presenter.jhtml?identifier=4574. Accessed September 30, 2008.
- Rollins CJ. Functional and Meal Replacement Foods. In Berardi RR, ed. Handbook of Nonprescription Drugs. 15th ed. Washington, DC: American Pharmacists Association; 2006:484-485.
- Soluble vs. Insoluble Fiber. MedlinePlus Web site. www.nlm.nih.gov/medlineplus/ency/article/002136.htm. Accessed September 30, 2008.
- Curry CE, Butler DM. Constipation. In Berardi RR, ed. Handbook of Nonprescription Drugs. 15th ed. Washington, DC: American Pharmacists Association; 2006:305-309.
- Metamucil Product Information. Metamucil Web site. www.metamucil.com. Accessed September 30, 2008.
- Fibercon Product Information. Fibercon Web site. www.fibercon.com. Accessed September 30, 2008.
- The Fiber Chronicles: Answers to Your Questions. Citrucel Product Information. www.citrucel.com/Ch5_FAQ.aspx#crush. Accessed September 30, 2008.