IS ANTIBIOTIC DEVELOPMENT DECLINING?

JANUARY 01, 2008

Treating the increase in drug-resistant and potentially deadly bacterial infections, particularly methicillin-resistant Staphylococcus aureus, may not be so easy. A major problem is that the pipeline for antibiotics is dwindling.

The Infectious Diseases Society of America indicated there were 16 new antibiotics approved by the FDA between 1983 and 1987, and 14 between 1988 and 1992, totaling an average of 3 a year. In the past 15 years, those figures have been steadily declining with only 5 new antibiotics getting FDA approval between 2003 and today.

Why the lack of new drugs? The pharmaceutical manufacturers are facing higher costs for new drugs that do not bring in the money when they enter the market. Therefore,the companies are investing funds in other types of medications for profits, including chronic diseases.

A new report, however, from the Pharmaceutical Research and Manufacturers of America found that pharmaceutical companies are currently testing 338 new drugs to help treat infectious disease, including 11 medicines and 4 vaccines to treat staphylococcal infections. The new medicines being tested are 146 vaccines to prevent diseases such as smallpox and staph; 83 antibiotics/antibacterials to treat infections such as pneumonia and tuberculosis; 75 antivirals to treat such viruses as hepatitis and influenza; and 25 antifungals.



SHARE THIS SHARE THIS
0

Become A RESPIMAT T.O.P. Performer 

Get to know RESPIMAT, the slow-moving mist inhaler from Boehringer Ingelheim Pharmaceuticals, Inc.

Watch the RESPIMAT video and test your knowledge with a short multiple-choice quiz. When you get all the answers right, you’ll receive a certificate naming you a RESPIMAT T.O.P. Performer. Why not check it out today?


Pharmacy Times Strategic Alliance
 

Pharmacist Education
Clinical features with downloadable PDFs


Next-Generation Pharmacist® Awards


3rd Annual Convenient Healthcare and Pharmacy Collaborative Conference


SIGN UP FOR THE PHARMACY TIMES NEWSLETTER
Personalize the information you receive by selecting targeted content and special offers.