Aromasin Offers Better Breast Cancer Survival Rates

AUGUST 01, 2006
Susan Farley

The Intergroup Exemestane Study (IES) yielded data showing that hormone- sensitive postmenopausal early breast cancer patients who switched from tamoxifen to Aromasin (exemestane) were 17% more likely to be alive and 25% less likely to see their cancer return than patients who remained on tamoxifen for 5 years. These study findings stem from almost 5 years of followup of the IES trial, a large, randomized, double-blind, multinational trial comparing 2352 patients taking Aromasin following tamoxifen therapy with 2372 patients remaining on tamoxifen therapy for 5 years. The IES produced early results that prompted the FDA and European regulatory approvals for Aromasin. These findings showed that 85% of patients in the trial were postmenopausal hormone receptor-positive, and those who switched to Aromasin reduced their risk of breast cancer recurrence by 35%, compared with the tamoxifen group. Previously, no difference in survival rates had been noted. Side effects were mild to moderate and included hot flashes, fatigue, arthralgia, headache, insomnia, and increased sweating.

Ms. Farley is a freelance medical writer based in Wakefield, RI.


Become a Respimat Top Performer 

Get to know RESPIMAT, the slow-moving mist inhaler from Boehringer Ingelheim Pharmaceuticals, Inc. 

Watch the RESPIMAT video and test your knowledge with a short multiple-choice quiz. When you get all the answers right, you’ll receive a certificate naming you a RESPIMAT T.O.P. Performer. Why not check it out today? 


Pharmacy Times Strategic Alliance

Pharmacist Education
Clinical features with downloadable PDFs

Next-Generation Pharmacist® Awards

3rd Annual Convenient Healthcare and Pharmacy Collaborative Conference

Personalize the information you receive by selecting targeted content and special offers.