Anna D. Garrett, PharmD, BCPS, CPP
Published Online: Tuesday, August 1, 2006

The National Comprehensive Cancer Network (NCCN) recently issued guidelines recommending inpatient prophylactic anticoagulation therapy with unfractionated heparin, low-molecularweight heparin (LMWH), or fondaparinux. The guidelines do not address outpatient prophylaxis, but they suggest immediate and long-term treatment once an episode of venous thromboembolism (VTE) occurs. The NCCN recommends 3 to 6 months of treatment for deep vein thrombosis, 6 to 12 months of treatment for pulmonary embolism, and indefinite treatment for patients with active cancer or persistent risk factors.

The NCCN recommends the use of LMWH or warfarin for long-term treatment and secondary prevention. Preliminary data suggest an improved survival benefit using LMWH, however. The new guidelines may be accessed at www.nccn.org/professionals/physician_gls/sPDF/vte.pdf.

Dr. Garrett is a clinical pharmacist practitioner at Cornerstone Health Care in High Point, NC.

Latest Articles
This weekly video program provides our readers with an in-depth review of the latest news, product approvals, FDA rulings and more.
Chronic kidney disease incidence has grown faster than many of its common comorbidities such as diabetes and hypertension, and medications may be an underappreciated driver of this growth.
President Barack Obama’s fiscal year 2017 budget proposal calls for an additional $1.1 billion to combat the nation’s spiraling opioid epidemic.
Baxter International is voluntarily recalling intravenous solution due to leaking containers and the potential for particulate matter.
Latest Issues