A study reported in the March 2006 issue of Headache determined that patients experiencing a migraine headache found greater relief in a shorter amount of time after taking 2 Excedrin Migraine tablets than patients taking 2 ibuprofen tablets. The data came from a double-blind, randomized, placebo-controlled study of 1555 migraine sufferers. Patients who took 2 Excedrin Migraine tablets when pain had reached a moderate intensity experienced significantly greater relief during the first 2 hours. Their pain relief was significantly better and was sustained longer (at the 3-and 4-hour postdose marks), when compared with the ibuprofen and placebo groups. It took Excedrin Migraine 45 minutes to work, compared with placebo; it took ibuprofen 90 minutes to work, compared with placebo. Significant relief was achieved 20 minutes sooner in the Excedrin Migraine group, compared with the ibuprofen group.
Ms. Farley is a freelance medical writer based in Wakefield, RI.
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
Clinical features with downloadable PDFs