Children whose fathers have a history of asthma are at greater risk of developing airway hyperresponsiveness (AHR). To assess the potential father-child asthma connection, the researchers reviewed data on 1041 children between the ages of 5 and 12 years enrolled in the Childhood Asthma Management Program. None of the participants had severe asthma.
In the 6 months prior to the 4-year study, which compared the long-term benefits of 3 inhaler asthma treatments, all of the children had manifested at least 1 asthma characteristic. To measure AHR severity, the children completed a series of tests that calculated the presence of methacholine in their bodies. The children's parents completed family history questionnaires, and the children were tested twice a year to assess the amount of air entering and leaving the lungs. The asthma- AHR parental connection appears to follow the paternal lineage.
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
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