New Indication for Rituxan

NOVEMBER 01, 2005
Susan Farley

Biogen Idec Inc and Genentech Inc, makers of the therapeutic antibody Rituxan, submitted a supplemental biologics license application with the FDA acknowledging a new indication for Rituxan—as a treatment for rheumatoid arthritis (RA) in patients who do not respond properly to anti-tumor necrosis factor (anti-TNF) therapy. The manufacturers based their claims on results of a 24-week, multicenter, randomized, double-blind, placebo-controlled phase 3 study known as REFLEX. The study measured patient response to a single course of 2 infusions of Rituxan plus a dose of methotrexate and found a statistical improvement of symptoms in 24 weeks, compared with a combination of placebo plus methotrexate. According to Genentech's Senior Vice President and Chief Medical Officer Hal Barron, MD, "Rituxan may provide a potential new treatment approach for the RA patient population with the greatest unmet medical need."

Ms. Farley is a freelance medical writer based in Wakefield, RI.




SHARE THIS SHARE THIS
0

Immunization Laws Around the Nation

Many areas of medicine that intersect with law and immunizations are associated with a very specific set of laws across the nation.  

 

Pharmacy Times Strategic Alliance
 

Pharmacist Education
Clinical features with downloadable PDFs


Next-Generation Pharmacist® Awards


3rd Annual Convenient Healthcare and Pharmacy Collaborative Conference


SIGN UP FOR THE PHARMACY TIMES NEWSLETTER
Personalize the information you receive by selecting targeted content and special offers.